Antihypertensive Drug Trial

import matplotlib.pyplot as plt
import numpy as np

np.random.seed(42)

# Blood pressure data
time_points = ['Baseline', 'Week 2', 'Week 4', 'Week 8', 'Week 12']
systolic_drug = np.array([145, 138, 132, 128, 125])
systolic_placebo = np.array([144, 143, 142, 141, 140])
diastolic_drug = np.array([92, 88, 85, 82, 80])
diastolic_placebo = np.array([91, 90, 90, 89, 89])
sys_err = np.array([5, 4, 4, 3, 3])
dia_err = np.array([3, 3, 2, 2, 2])

fig, (ax1, ax2) = plt.subplots(1, 2, figsize=(12, 5), facecolor='#0a0a0f')

for ax in [ax1, ax2]:
    ax.set_facecolor('#0a0a0f')

x = np.arange(len(time_points))

# Systolic
ax1.errorbar(x, systolic_drug, yerr=sys_err, fmt='o-', color='#27D3F5',
             ecolor='#27D3F5', elinewidth=2, capsize=5, markersize=10,
             markeredgecolor='white', linewidth=2, label='Drug', alpha=0.9)
ax1.errorbar(x, systolic_placebo, yerr=sys_err, fmt='s--', color='#F5276C',
             ecolor='#F5276C', elinewidth=2, capsize=5, markersize=8,
             markeredgecolor='white', linewidth=2, label='Placebo', alpha=0.9)
ax1.axhline(y=130, color='#6CF527', linestyle=':', linewidth=2, 
            label='Normal (<130)', alpha=0.7)
ax1.fill_between(x, 90, 120, color='#6CF527', alpha=0.1)

ax1.set_xlabel('Time Point', fontsize=11, color='white', fontweight='500')
ax1.set_ylabel('Systolic BP (mmHg)', fontsize=11, color='white', fontweight='500')
ax1.set_title('Systolic Blood Pressure', fontsize=13, color='white', fontweight='bold')
ax1.set_xticks(x)
ax1.set_xticklabels(time_points, rotation=45, ha='right')
ax1.legend(facecolor='#1a1a2e', edgecolor='#333', labelcolor='white', fontsize=9)
ax1.tick_params(colors='#94a3b8', labelsize=9)
ax1.set_ylim(110, 160)
ax1.grid(True, alpha=0.2, color='#4a4a6a')

# Diastolic
ax2.errorbar(x, diastolic_drug, yerr=dia_err, fmt='o-', color='#27D3F5',
             ecolor='#27D3F5', elinewidth=2, capsize=5, markersize=10,
             markeredgecolor='white', linewidth=2, label='Drug', alpha=0.9)
ax2.errorbar(x, diastolic_placebo, yerr=dia_err, fmt='s--', color='#F5276C',
             ecolor='#F5276C', elinewidth=2, capsize=5, markersize=8,
             markeredgecolor='white', linewidth=2, label='Placebo', alpha=0.9)
ax2.axhline(y=80, color='#6CF527', linestyle=':', linewidth=2, 
            label='Normal (<80)', alpha=0.7)
ax2.fill_between(x, 60, 80, color='#6CF527', alpha=0.1)

ax2.set_xlabel('Time Point', fontsize=11, color='white', fontweight='500')
ax2.set_ylabel('Diastolic BP (mmHg)', fontsize=11, color='white', fontweight='500')
ax2.set_title('Diastolic Blood Pressure', fontsize=13, color='white', fontweight='bold')
ax2.set_xticks(x)
ax2.set_xticklabels(time_points, rotation=45, ha='right')
ax2.legend(facecolor='#1a1a2e', edgecolor='#333', labelcolor='white', fontsize=9)
ax2.tick_params(colors='#94a3b8', labelsize=9)
ax2.set_ylim(70, 100)
ax2.grid(True, alpha=0.2, color='#4a4a6a')

for ax in [ax1, ax2]:
    for spine in ax.spines.values():
        spine.set_color('#333333')

plt.suptitle('Antihypertensive Drug Trial Results', fontsize=14, 
             color='white', fontweight='bold', y=1.02)
plt.tight_layout()
plt.show()